Director, Obesity Metabolism and Muscle Disease

Company: Regeneron Pharmaceuticals, Inc.
Location: Tarrytown
Posted on: January 15, 2026

Job Description:

Regeneron seeks a leader in skeletal muscle physiology and biology to head its research and therapeutic development team. This group uses various cutting-edge molecular cell biology, genetic, and transcriptomic profiling techniques, as well as genetic animal models to understand muscle physiology and pathophysiology at the cellular and molecular level. This group is committed to understanding the fundamental molecular mechanisms of muscle development and function aiming to identify new therapeutic and diagnostic platforms for a range of muscle degenerative diseases and inflammatory conditions. This leadership role requires a deep expertise in skeletal muscle biology, preferably with some experience in translational research and therapeutic development. The successful candidate will possess excellent communication skills and the ability to inspire multidisciplinary teams to achieve ambitious scientific goals. Specifically, they provide strategic guidance, driving technological advancement, and critically assessing data and projects across the preclinical scientific team. In addition, the candidate would be able to participate and contribute to clinical trial design and work with key opinion leaders. The position encompasses progressing drug targets from discovery through clinical development, as well as representation of Regenerons Muscle Therapeutics strategy to both Senior Leadership and externally. A Typical Day May Include: Establish the strategic vison and framework for muscle biology research, including identification of new therapeutic targetsparticularly for genetic diseasesand incorporation of emerging technologies and scientific developments into the research pipeline. Work and direct a team of scientists to design complex in vitro (cell culture) and in vivo (innovative animal model) studies investigating muscle development, physiological and metabolic function, regeneration, and disease mechanisms. Supervise talented scientists, research associates, and technical professionals to deliver high-caliber, rigorous, and impactful research results. Careful analysis of results and Lead and set clear short- and long-term objectives to ensure the production of quality scientific output are in alignment with team and therapeutic area goals. Oversee project workflows, making critical decisions regarding project continuation, and facilitating the efficient transition of drug targets through developmental stages. Actively engage in cross-functional, and leadership meetings, contributing expertise in muscle cell biology and advocating the teams vision. Work with Global Development and Clinical teams to deliver on innovative trial design, analysis of results with an aim of speed to approval. Work with KOL and advocacy groups to elevate our standing in the field and our therapeutic approaches. Promote collaboration between therapeutic areas and technology groups, fostering relationships and utilizing resources to enhance research outcomes. Mentor team members by supporting their professional growth and development. Review and authorize muscle-related documentation, including regulatory submissions, manuscripts, and contracts. This role might be for you if you have: Experience with cutting-edge technologies and their application to muscular disorders such as genetic targeting with siRNA, shRNA, CRISPR/Cas9, AAVs is advantageous Exceptional written and verbal communication skills, with the ability to articulate scientific concepts and strategic vision. Proven leadership, managerial, and mentorship abilities and the ability to work in a matrix environment. Experience in group administration, including budget and organizational management. Exposure to drug development or regulated activities is highly desirable and working in a matrix organization. Strong professional network, publication record, and national/international reputation preferred. To be considered for this position, we are looking for: PhD in Molecular Biology, Biomedicine, Biochemistry, Human Biology, Human Skeletal or Exercise Physiology, or a related discipline. Extensive cellular and molecular biology expertise in muscle biology and metabolism is desirable. Minimum of 6 years post-PhD experience and at least 5 years in industry or translational settings preferred. Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other countries specific benefits, please speak to your recruiter. Please be advised that at Regeneron, we believe we are most successful and work best when we are together. For that reason, many of Regenerons roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about Regenerons on-site policy and expectations for your role and your location. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business. For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location. Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc. Salary Range (annually) $202,000.00 - $336,600.00

Keywords: Regeneron Pharmaceuticals, Inc., Brick , Director, Obesity Metabolism and Muscle Disease, Science, Research & Development , Tarrytown, New Jersey